Projects per year
Personal profile
About
Dr. Ruth Borghaei is a Professor in the Department of Biomedical Sciences. She is Director of the Molecular Basis of Medicine course in the Masters in Biomedical Sciences program and also teaches molecular biology and genetics to those students and to first-year DO students. Dr. Borghaei's research interest is in the homeostatic regulation of gene expression, particularly in response to inflammation.
Dr. Borghaei has also served as reviewer for a number of peer-reviewed journals and grant-making panels for the NIH and other organizations.
Related documents
Education/Academic qualification
Microbiology and Immunology, PhD, Temple University School of Medicine
… → 1992
Microbiology, BS, University of Maine
… → 1987
ASJC Scopus Subject Areas
- Biochemistry, medical
- Molecular Biology
Disciplines
- Molecular Biology
- Medical Biochemistry
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Regulation of DNA methylation and demethylation by inflammatory cytokines
Borghaei, R. (PI)
1/1/15 → …
Project: Research project
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Effects of nicotine and glucose on production of inflammatory mediators in response to IL-1 and LPS in human gingival fibroblasts and CAL27 oral cancer cells
Borghaei, R. (PI)
1/1/10 → 1/1/11
Project: Research project
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Transcriptional regulation of matrix metalloproteinase 3
Borghaei, R. (PI)
1/1/04 → 1/1/10
Project: Research project
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IL-1 Regulation of MMP Genes in Human Gingival Fibroblasts
Borghaei, R. (PI)
1/1/97 → 1/1/03
Project: Research project
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IL-1 Regulation of MMP Genes in Human Gingival Fibroblasts
Borghaei, R. (PI)
1/1/95 → 1/1/97
Project: Research project
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Transcriptional regulation of c-Jun expression during late G1/S in normal human cells is lost in human tumor cells
Borghaei, R. C., Yumet, G., Peña, A., Soprano, D. R. & Soprano, K. J., Sep 2994, In: Oncogene. 9Research output: Contribution to journal › Article › peer-review
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Assessing the effects of a novel metalloprotease inhibitor, extracellular matrix protection factor-2, on primary human gingival fibroblast's metabolic viability as determined by total protein production
Maloney, T., Mattioli, P., Laird, P., Musiol, J., Popper, H., Otto, A., Green, K., Shamseddin, S., Borghaei, R. & D'Angelo, M., May 10 2021.Research output: Contribution to conference › Presentation
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Measurement of collagen metabolism and metalloprotease production demonstrates that primary human gingival fibroblasts retain inflamed tissue profile in serum free culture
Musiol, J., Laird, P., Mattioli, P., Maloney, T., Popper, H., Otto, A., Isaac, T., Nguyen, S., Morris, G., Shamseddin, S., Green, K., Borghaei, R. & D'Angelo, M., May 10 2021.Research output: Contribution to conference › Presentation
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Interleukin 1β and Prostaglandin E2 Affect Expression of DNA Methylating and Demethylating Enzymes in Human Gingival Fibroblasts
Seutter, S., Winfield, J., Esbitt, A., Snyder, S., Magner, A., Kim, K., Carcuffe, C., Schmoyer, J., Kamrani, P., Mercando, J., Shamseddin, S. M., Green, K. & Borghaei, R. C., Jan 1 2020, In: International Immunopharmacology. 78Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Extracellular Matrix Protection Factor-2 Reduces Collagen Degradation in Primary Serum-Free Cultures of Inflamed Human Gingival Fibroblasts
Isaac, T., Mattioli, P., Chmielewski, S., Buckley, A., Seutter, S., Gambardella, E., Green, K., Shamseddin, S., Borghaei, R., Selim, A. & D'Angelo, M., May 9 2018.Research output: Contribution to conference › Presentation
Activities
- 3 Membership of network
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American Society for Biochemistry and Molecular Biology (External organization)
Ruth C. Borghaei (Member)
2000 → …Activity: Membership › Membership of network
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Sigma Xi - PCOM Chapter (External organization)
Ruth C. Borghaei (Member)
2000 → …Activity: Membership › Membership of network
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American Society of Genetics (External organization)
Ruth C. Borghaei (Member)
2000 → …Activity: Membership › Membership of network