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Apocynin Exerts Dose-Dependent Cardioprotective Effects by Attenuating Reactive Oxygen Species in Ischemia/Reperfusion

  • Qian Chen
  • , Woodworth C. Parker
  • , Issachar Devine
  • , Regina Ondraskik
  • , Tsion Habtamu
  • , Kyle Bartol
  • , Brendan Casey
  • , Harsh Patel
  • , William Chau
  • , Tarah Kuhn

Research output: Contribution to journalArticlepeer-review

Abstract

Ischemia/reperfusion results in cardiac contractile dysfunction and cell death partly due to increased reactive oxygen species and decreased endothelial-derived nitric oxide bioavailability. NADPH oxidase normally produces reactive oxygen species to facil

Original languageAmerican English
JournalCardiovascular Pharmacology
Volume5
StatePublished - Jan 1 2016

Disciplines

  • Physiology

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