Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis

Andrew LoPolito; Tala Mourabet; Huda Syed; Catherine T Brown; Launick Saint-Fort; Michael A Horst; Lindsey Perea

Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis

Andrew LoPolito, Tala Mourabet, Huda Syed, Catherine T Brown, Launick Saint-Fort, Michael A Horst, Lindsey Perea

Department of Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to investigate this further through a retrospective, single institutional study performed from January 2018 through June 2021, utilizing data from patients presenting to a Level 1 Trauma Center as a trauma activation. We observed less frequent VTE development in the marijuana-positive group compared to the marijuana-negative group, with patient thromboelastography revealing a longer mean R-time in the marijuana-positive group. Overall occurrence of VTE was too low for definitive conclusions, but a trend toward reduction in VTE frequency among marijuana users compared to nonusers was noted. More studies with larger populations and more VTE occurrences are needed to confirm a potential correlation between marijuana use and VTE development

Original language	American English
Journal	The American surgeon
Volume	89
State	Published - Feb 2023

Disciplines

Trauma

Cite this

@article{f161eef444334ccfa80f7ce751b2d605,

title = "Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis",

abstract = " Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to investigate this further through a retrospective, single institutional study performed from January 2018 through June 2021, utilizing data from patients presenting to a Level 1 Trauma Center as a trauma activation. We observed less frequent VTE development in the marijuana-positive group compared to the marijuana-negative group, with patient thromboelastography revealing a longer mean R-time in the marijuana-positive group. Overall occurrence of VTE was too low for definitive conclusions, but a trend toward reduction in VTE frequency among marijuana users compared to nonusers was noted. More studies with larger populations and more VTE occurrences are needed to confirm a potential correlation between marijuana use and VTE development ",

author = "Andrew LoPolito and Tala Mourabet and Huda Syed and Brown, {Catherine T} and Launick Saint-Fort and Horst, {Michael A} and Lindsey Perea",

year = "2023",

month = feb,

language = "American English",

volume = "89",

journal = "The American surgeon",

}

TY - JOUR

T1 - Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis

AU - LoPolito, Andrew

AU - Mourabet, Tala

AU - Syed, Huda

AU - Brown, Catherine T

AU - Saint-Fort, Launick

AU - Horst, Michael A

AU - Perea, Lindsey

PY - 2023/2

Y1 - 2023/2

N2 - Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to investigate this further through a retrospective, single institutional study performed from January 2018 through June 2021, utilizing data from patients presenting to a Level 1 Trauma Center as a trauma activation. We observed less frequent VTE development in the marijuana-positive group compared to the marijuana-negative group, with patient thromboelastography revealing a longer mean R-time in the marijuana-positive group. Overall occurrence of VTE was too low for definitive conclusions, but a trend toward reduction in VTE frequency among marijuana users compared to nonusers was noted. More studies with larger populations and more VTE occurrences are needed to confirm a potential correlation between marijuana use and VTE development

AB - Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to investigate this further through a retrospective, single institutional study performed from January 2018 through June 2021, utilizing data from patients presenting to a Level 1 Trauma Center as a trauma activation. We observed less frequent VTE development in the marijuana-positive group compared to the marijuana-negative group, with patient thromboelastography revealing a longer mean R-time in the marijuana-positive group. Overall occurrence of VTE was too low for definitive conclusions, but a trend toward reduction in VTE frequency among marijuana users compared to nonusers was noted. More studies with larger populations and more VTE occurrences are needed to confirm a potential correlation between marijuana use and VTE development

UR - https://doi.org/10.1177/00031348231157889

M3 - Article

VL - 89

JO - The American surgeon

JF - The American surgeon

ER -

Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis

Abstract

Disciplines

Other files and links

Cite this