Effect of erythrocytes of androgens on 2,3-diphosphoglycerate in patients with chronic obstructive pulmonary disease

John P. Simelaro, Michael Venditto, M. Ghens

Research output: Contribution to journalArticlepeer-review

Abstract

Because androgen therapy is known to increase 2,3-diphosphoglycerate in the erythrocytes of patients with chronic renal failure, the possibility that it might have a similar effect on patients with chronic obstructive pulmonary disease appeared worth investigating. Results of a small study appear promising, with improvement in stress tolerance and general well-being. Pulmonary function was not improved, and the severity of pulmonary disease was not affected, but further investigation of the treatment appears to be warranted.

Original languageAmerican English
JournalChest
Volume76
StatePublished - Jan 1 1980

Keywords

  • 2
  • 3 diphosphoglyceric acid
  • androgen
  • nandrolone decanoate
  • adult
  • aged
  • blood analysis
  • blood and hemopoietic system
  • chronic obstructive lung disease
  • drug efficacy
  • electrocardiography
  • erythrocyte
  • heart
  • human
  • human cell
  • intramuscular drug administration
  • lung function
  • major clinical study
  • respiratory system
  • therapy
  • Diphosphoglyceric Acids
  • Erythrocytes
  • Female
  • Lung Diseases
  • Obstructive
  • Male
  • Middle Age
  • Nandrolone

Disciplines

  • Medicine and Health Sciences

Cite this