Effects of protein kinase C broad spectrum inhibitor Gö 6983 on real-time blood nitric oxide and hydrogen peroxide release in femoral artery/vein ischemia and reperfusion

Kyle D. Bartol; Kerry-Anne Perkins; Qian Chen; Lindon H. Young

Effects of protein kinase C broad spectrum inhibitor Gö 6983 on real-time blood nitric oxide and hydrogen peroxide release in femoral artery/vein ischemia and reperfusion

Kyle D. Bartol, Kerry-Anne Perkins, Qian Chen, Lindon H. Young

Department of Bio-Medical Sciences (PCOM)

Research output: Other contribution

Abstract

BACKGROUND: Vascular endothelial dysfunction is one of the earliest recognizable events under hyperglycemic conditions. It is characterized by decreased endothelium-derived nitric oxide (NO) and increased oxidative stress, such as superoxide and hydrogen peroxide (H2O2). However, the real-time changes in blood NO and H2O2 levels under acute hyperglycemia have not been evaluated.

Original language	American English
State	Published - Apr 27 2011

Keywords

Hyperglycemia
Protein Kinase C
Endothelium
Ischemia
Reperfusion

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Effects of protein kinase C broad spectrum inhibitor Gö 6983 on rFinal published version, 7.99 KBLicense: CC BY

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@misc{60f6649412094f95a9cf9d98e42e5317,

title = "Effects of protein kinase C broad spectrum inhibitor G{\"o} 6983 on real-time blood nitric oxide and hydrogen peroxide release in femoral artery/vein ischemia and reperfusion",

abstract = " BACKGROUND: Vascular endothelial dysfunction is one of the earliest recognizable events under hyperglycemic conditions. It is characterized by decreased endothelium-derived nitric oxide (NO) and increased oxidative stress, such as superoxide and hydrogen peroxide (H2O2). However, the real-time changes in blood NO and H2O2 levels under acute hyperglycemia have not been evaluated.",

keywords = "Hyperglycemia, Protein Kinase C, Endothelium, Ischemia, Reperfusion",

author = "Bartol, {Kyle D.} and Kerry-Anne Perkins and Qian Chen and Young, {Lindon H.}",

year = "2011",

month = apr,

day = "27",

language = "American English",

type = "Other",

}

TY - GEN

T1 - Effects of protein kinase C broad spectrum inhibitor Gö 6983 on real-time blood nitric oxide and hydrogen peroxide release in femoral artery/vein ischemia and reperfusion

AU - Bartol, Kyle D.

AU - Perkins, Kerry-Anne

AU - Chen, Qian

AU - Young, Lindon H.

PY - 2011/4/27

Y1 - 2011/4/27

N2 - BACKGROUND: Vascular endothelial dysfunction is one of the earliest recognizable events under hyperglycemic conditions. It is characterized by decreased endothelium-derived nitric oxide (NO) and increased oxidative stress, such as superoxide and hydrogen peroxide (H2O2). However, the real-time changes in blood NO and H2O2 levels under acute hyperglycemia have not been evaluated.

AB - BACKGROUND: Vascular endothelial dysfunction is one of the earliest recognizable events under hyperglycemic conditions. It is characterized by decreased endothelium-derived nitric oxide (NO) and increased oxidative stress, such as superoxide and hydrogen peroxide (H2O2). However, the real-time changes in blood NO and H2O2 levels under acute hyperglycemia have not been evaluated.

KW - Hyperglycemia

KW - Protein Kinase C

KW - Endothelium

KW - Ischemia

KW - Reperfusion

UR - https://digitalcommons.pcom.edu/research_day/research_day/research/18

M3 - Other contribution

ER -

Effects of protein kinase C broad spectrum inhibitor Gö 6983 on real-time blood nitric oxide and hydrogen peroxide release in femoral artery/vein ischemia and reperfusion

Abstract

Keywords

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