Evaluation of narcotic analgetic activity using a cat tail-flick procedure

Frederick J. Goldstein, R. T. Malseed

Research output: Contribution to journalArticlepeer-review

Abstract

A classical narcotic analgetic testing procedure, the thermal-induced rat tail-flick, has been adapted for utilization in cats. The feline tail-flick method is simple to perform and is a sensitive, specific, and reproducible test for evaluation of narcotic analgetic activity. It is readily applicable to chronic investigations in this species. © 1979.

Original languageAmerican English
JournalJournal of pharmacological methods
Volume2
StatePublished - Jan 1 1979

Keywords

  • Cat
  • Narcotic analgetics
  • Tail flick
  • animal experiment
  • biological model
  • central nervous system
  • morphine
  • morphinomimetic agent
  • naloxone
  • narcotic analgesia
  • narcotic analgesic agent
  • pentobarbital
  • salicylate sodium
  • subcutaneous drug administration
  • tail flick test

Disciplines

  • Medicine and Health Sciences

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