GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus

Diana Peterson; Martha E Bickford; Brett R. Schofield

doi:10.1002/cne.10387

GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus

Diana Peterson, Martha E Bickford, Brett R. Schofield

Department of Bio-Medical Sciences (PCOM)

Research output: Contribution to journal › Article › peer-review

Abstract

γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei. J. Comp. Neurol. 453:45–56, 2002. © 2002 Wiley-Liss, Inc.

Original language	American English
Journal	Journal of Comparative Neurology
Volume	453
DOIs	https://doi.org/10.1002/cne.10387
State	Published - Sep 2002

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Medicine and Health Sciences

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title = "GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus",

abstract = " γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei. J. Comp. Neurol. 453:45–56, 2002. {\textcopyright} 2002 Wiley-Liss, Inc.",

author = "Diana Peterson and Bickford, {Martha E} and Schofield, {Brett R.}",

note = "Diana L. Coomes , Martha E. Bickford , Brett R. Schofield , Corresponding Author Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, Kentucky 40202 Department of Anatomical Sciences and Neurobiology, University of Louisville, 500 S.",

year = "2002",

month = sep,

doi = "10.1002/cne.10387",

language = "American English",

volume = "453",

journal = "Journal of Comparative Neurology",

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TY - JOUR

T1 - GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus

AU - Peterson, Diana

AU - Bickford, Martha E

AU - Schofield, Brett R.

N1 - Diana L. Coomes , Martha E. Bickford , Brett R. Schofield , Corresponding Author Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, Kentucky 40202 Department of Anatomical Sciences and Neurobiology, University of Louisville, 500 S.

PY - 2002/9

Y1 - 2002/9

N2 - γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei. J. Comp. Neurol. 453:45–56, 2002. © 2002 Wiley-Liss, Inc.

AB - γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei. J. Comp. Neurol. 453:45–56, 2002. © 2002 Wiley-Liss, Inc.

UR - https://doi.org/10.1002/cne.10387

U2 - 10.1002/cne.10387

DO - 10.1002/cne.10387

M3 - Article

VL - 453

JO - Journal of Comparative Neurology

JF - Journal of Comparative Neurology

ER -

GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus

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