Genetic Inactivation of Chlamydia trachomatis Inclusion Membrane Protein CT228 Alters MYPT1 Recruitment, Extrusion Production, and Longevity of Infection

TY - JOUR

T1 - Genetic Inactivation of Chlamydia trachomatis Inclusion Membrane Protein CT228 Alters MYPT1 Recruitment, Extrusion Production, and Longevity of Infection

AU - Shaw, Jennifer H.

AU - Key, Charlotte E.

AU - Snider, Timothy A.

AU - Sah, Prakash

AU - Shaw, Edward I.

AU - Fisher, Derek J.

AU - Lutter, Erika I.

N1 - Chlamydia trachomatis is an obligate intracellular pathogen with global health and economic impact. Upon infection, C. trachomatis resides within a protective niche, the inclusion, wherein it replicates and usurps host cell machinery and resources. The inclusion membrane is the key host-pathogen interface that governs specific protein-protein interactions to manipulate host signaling pathways.

PY - 2018/11/30

Y1 - 2018/11/30

UR - https://www.frontiersin.org/articles/10.3389/fcimb.2018.00415/full

U2 - 10.3389/fcimb.2018.00415

DO - 10.3389/fcimb.2018.00415

M3 - Article

VL - 8

JO - Frontiers in Cellular and Infection Microbiology

JF - Frontiers in Cellular and Infection Microbiology

ER -