Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis

Mula Ramanjaneya; Rangaiah Shashidharamurthy; Shashidharamurthy Taval

Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis

Mula Ramanjaneya, Rangaiah Shashidharamurthy, Shashidharamurthy Taval

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Abstract

Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the development of RA. Therefore, in this article we have highlighted the distinct functions of TNF-α during pathogenesis of RA

Original language	American English
Journal	Advances in Bioscience and Biotechnology
Volume	4
State	Published - Jan 1 2013

Keywords

Cytokines
Tumor Necrosis Factor-α
Rheumatoid Arthritis
Inflammation

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Multifacted Role of TNF- During the Pathogenesis of Rheumatoid AFinal published version, 201 KBLicense: CC BY

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title = "Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis",

abstract = " Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the development of RA. Therefore, in this article we have highlighted the distinct functions of TNF-α during pathogenesis of RA",

keywords = "Cytokines, Tumor Necrosis Factor-α, Rheumatoid Arthritis, Inflammation",

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AU - Ramanjaneya, Mula

AU - Shashidharamurthy, Rangaiah

AU - Taval, Shashidharamurthy

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the development of RA. Therefore, in this article we have highlighted the distinct functions of TNF-α during pathogenesis of RA

AB - Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the development of RA. Therefore, in this article we have highlighted the distinct functions of TNF-α during pathogenesis of RA

KW - Cytokines

KW - Tumor Necrosis Factor-α

KW - Rheumatoid Arthritis

KW - Inflammation

UR - https://digitalcommons.pcom.edu/scholarly_papers/288

M3 - Article

VL - 4

JO - Advances in Bioscience and Biotechnology

JF - Advances in Bioscience and Biotechnology

ER -

Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis

Abstract

Keywords

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