Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle.

TY - JOUR

T1 - Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle.

AU - Barman, Scott A.

AU - Zhu, Shu

AU - White, Richard E.

N1 - Signaling mechanisms that elevate cyclic AMP (cAMP) activate large-conductance, calcium- and voltage-activated potassium (BK Ca) channels in pulmonary vascular smooth muscle and cause pulmonary vasodilatation. BK Ca channel modulation is important in the regulation of pulmonary arterial pressure, and inhibition (closing) of the BK Ca channel has been implicated in the development of pulmonary vasoconstriction.

PY - 2004/1/1

Y1 - 2004/1/1

UR - https://augusta.pure.elsevier.com/en/publications/protein-kinase-c-inhibits-bksubcasub-channel-activity-in-pulmonar

U2 - 10.1152/ajplung.00207.2003

DO - 10.1152/ajplung.00207.2003

M3 - Article

VL - 286

JO - American Journal of Physiology-lung Cellular and Molecular Physiology

JF - American Journal of Physiology-lung Cellular and Molecular Physiology

ER -