The impact of medication therapy management services on pediatric patients with medical complexities

Charisma Osuagwu, Erica Wong, Savion Carswell, Sophia Jenkins, Xinyu Wang, Yujin Kim

Research output: Contribution to conferencePresentation



Medication Therapy Management (MTM) is a service provided by healthcare providers to ensure the best medical outcomes, particularly for those with multiple chronic conditions. It is often provided for senior populations supported under the Centers for Medicare & Medicaid Services. Studies show that patients provided with MTM services have higher medication adherence rates and experience fewer complications. However, there are few studies on MTM counseling in pediatric populations. In this literature review study, we investigated the potential impact of MTM services for underserved pediatric populations with chronic conditions or disabilities who are likely to benefit from MTM services.


A multivariate review analysis was performed. Data was sourced from National Library of Medicine Pubmed and Google Scholar for the collection of primary literature. Inclusion criteria included terms such as pediatric population (patients less than 20 years of age), children with medical complexities or children with disabilities. MTM eligibility, MTM intervention, medication adherence, barriers to adherence were also included in search criteria. The chronic disease states this study included are: epilepsy, cystic fibrosis, leukemia, asthma, and diabetes. Exclusion criteria were the adult population over 20 years old, and ‘acute care’.


A total of 17 primary research articles that met the criteria were identified in this literature review study. The articles were sorted into four criteria based on whether they included: children with disabilities, chronic diseases and medical complexities, multiple medication use complications and interventions, and population health disparities. Thirteen articles satisfied children with disabilities as the target population (age less than 18 years old with chronic physical/developmental/behavioral/emotional conditions that require health interventions). Eleven articles satisfied population health disparities: featuring notable differences in opportunities to achieve optimal health experienced by socially disadvantaged populations. Eight articles satisfied medication use complications and interventions, presenting an ongoing need and use of multiple prescriptions. Seven articles represented chronic diseases and medical complexities: chronic conditions with functional limitations lasting more than a year.


In total, there were seven articles found that discussed MTM service and medication adherence in the special population that required multiple medication therapy. The disease states that were focused on included epilepsy, cystic fibrosis, leukemia, asthma, and diabetes. Of the articles, two had documented MTM services and adherence monitoring for their patient population. The papers demonstrated that patients with chronic diseases, such as asthma and diabetes in adolescents, received benefits from MTM service and an increased rate of medication adherence. Therefore, our review emphasizes the need for further research on the impact of MTM service in a socially vulnerable population.

Original languageAmerican English
StatePublished - May 11 2023


  • Pediatrics
  • Medication Therapy Management
  • MTM
  • Adherence
  • Disabilities
  • Medical Complexities


  • Medicine and Health Sciences
  • Pediatrics
  • Pharmacy and Pharmaceutical Sciences

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