Abstract
Stimulant medication and behavioral treatments are evidence-based for children with attention-deficit/hyperactivity disorder, but the combination of the 2 treatments has been understudied. In this investigation, methylphenidate (MPH) was crossed with 2 levels of behavior modification (BMOD) in a summer treatment program. Twenty-seven children with attention-deficit/hyperactivity disorder, aged 6-12, participated. Children received placebo and 3 doses of transdermal MPH (12.5 cm2, 25.0 cm2, and 37.5 cm 2). BMOD was implemented on alternating weeks. Both treatments produced large and significant effects. Combined treatment was superior to either treatment alone. The effects of transdermal MPH were comparable to those found in this setting in previous studies with multiple stimulant medications and formulations. Consistent with other research, low doses of MPH-even lower than in previous studies-yielded enhanced effects in combination with behavior modification. Copyright 2005 by the American Psychological Association.
Original language | American English |
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Journal | Experimental and Clinical Psychopharmacology |
Volume | 13 |
State | Published - Jan 1 2005 |
Keywords
- Administration
- Attention Deficit Disorder with Hyperactivity
- Attention deficit hyperactivity disorder
- Behavior
- Behavior Therapy
- Behavioral treatment
- Central Nervous System Stimulants
- Child
- Combined Modality Therapy
- Combined treatment
- Cutaneous
- Dose-Response Relationship
- Drug
- Humans
- Methylphenidate
- Psychiatric Status Rating Scales
- Psychological
- Stress
- adolescent
- article
- attention deficit disorder
- behavior modification
- clinical article
- clinical trial
- controlled clinical trial
- controlled study
- dose response
- double blind procedure
- emotionality
- female
- human
- insomnia
- low drug dose
- male
- motor dysfunction
- placebo
- randomized controlled trial
- side effect
- skin irritation
- skin manifestation
- summer
- tic
- treatment outcome
Disciplines
- Psychology